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Don’t Fear the PPI (but Don’t Take it if You Don’t Need It)

Much has been touted in the media and social media about the recent proton pump inhibitor (PPI) study in JAMA relating long term use of these drugs to chronic kidney disease.  There is so much hype that I thought it important to take a closer look.

The study in JAMA is only available to the public as an abstract, which means the authors condensed an 8 page document into 7 paragraphs (basically a half-page).  This is standard…you  have to PAY to be able to read the whole article, and the abstract doesn’t tell the whole story.   Your old pal, an …

Intern Jesse’s Internship Debriefing

This is the paper Intern Jesse (now Associate Producer Jesse) had to turn in to his university to get credit for his rotation with us.  He did a great job, and deserved the solid C+ we gave him for his efforts.  🙂


Internship Reflection

“It’s Weird Medicine, the first, and still only, uncensored medical show in the history of radio!”  In the last few months, I’ve heard those words more times than I can count.  That one phrase, along with a hefty majority of the rest of the introduction, is burned into my …

Flatus Flute

Well, our friend on Twitter @SonOfFritz gave us this artwork for the whistling rectal rocket  novelty item, being produced by our friend Danny in Canada.   If the dumb things never make it to market, this cover art made me very, very happy.


Please Help Our Friend Tracy DeMarzo

Our friend, Tracy DeMarzo (many of you know her as Rick Shapiro’s wife) is battling breast cancer and has a GoFundMe account for her surgery and reconstruction.   To quote Tracy:

For those of you that know me, you know that I have great self-body-image. And yes, many of you have seen my boobs! Which makes me love them more.  I have been on stages as a stripper, I have been to Fantasy Fest in Key West, wet t-shirt contests, naked piano dancing.. it was all me. But more importantly, my breasts …

RexDart Update

It is with great sadness that I report that our friend of many months, RexDart, AKA Jeff Zurio, succumbed to his metastatic cancer earlier in the month.  Fred from Brooklyn and I had kept in touch with him and when I last spoke with him he was in good spirits with good pain control.  He had friends in El Paso who were going to actually care for him so he wouldn’t be alone.   After that phone call, we lost all contact with Jeff.

One thing Jeff told me (many times, actually) was that the support, both financially and emotionally, from …

You Don’t Want to Miss This!

Catch a Rising Star
Ocean State Theatre

Rob Bartlett & Tony Powell
Saturday, June 27 at 7:30pm
$42 – Standard Seating
$52 – Premium Seating

(*show contains adult language; 18+)

(comedian Rob Bartlett)

(comedian Tony Powell)

Rob started in stand-up comedy at Richard M. Dixon’s White House Inn, a talent showcase club on New York’s Long Island run by the presidential look-alike. He has headlined at the Sands Hotel and Casino in Las Vegas, Atlantic City’s Tropicana and Hilton …

RexDart Update

We have a listener who has been battling terminal bladder cancer since 2011. He’s had to try to continue to work just to keep the lights on despite horrific intractable pain, but hasn’t had a full time job since being laid off in 2012. A few months ago he told me “i’m already $100 away from being homeless. At this point I long for the relief that death will bring.”

Recently he was admitted with intractable bleeding from his bladder, causing blood clots that obstructed his urethra, causing horrific pain. A large catheter with three tubes in it did continuous …

Abscopal Effect and Malignant Melanoma

[This one is a rare effect, but if they can just figure out how to trigger it consistently (research is ongoing) this would be a kickass weapon in the war against malignant melanoma and some other cancers.   A more general article on the abscopal effect can be found on Wikipedia, but here’s a quickie from Oncology Nurse Advisor.   –dr steve]

A recent melanoma case featuring the abscopal effect, in which local radiotherapy delivered to a single tumor results in the regression of metastatic cancer at a distance from the irradiated site, may lay the groundwork …

Measles and Multiple Myeloma

[Another interesting idea…if you know someone with refractory multiple myeloma, they may qualify for a clinical trial in vaccine therapy (take THAT, anti-vaxxers!)  –dr steve]

from cnn.com

A woman with an incurable cancer is now in remission, thanks, doctors say, to a highly concentrated dose of the measles virus.

For 10 years, Stacy Erholtz, 49, battled multiple myeloma, a deadly cancer of the blood. Doctors at the Mayo Clinic say she had received every type of chemotherapy drug available for her cancer and had undergone two stem cell transplants, only to relapse time …

Striking Results With T-Cell Immunotherapy in Cervical Cancer

[I used to say we were 100 years away from a more generalized approach to cancer therapy.  In the end, barring some unforeseen breakthrough, cancer “cures” will come from the realm of immunology.  The immune system is perfectly appointed to eradicate cancer cell by cell, molecule by molecule, but it only works if it actually recognizes the cancer as abnormal.  Turning on the immune system to recognize cancer cells as foreign is the purpose of a lot of research right now and this is the outcome of a small pilot study.  This makes me think the time horizon is …

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