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Non-pseudoscience Cancer Cures Steve's Blog

Cutting Through the Hype: The Cancer Cure Story of June 2022

This is the original study where all the “hoopla,” if I may use “salty” language, arose. Though the title is rather nondescript, the result is promising. I’ll annotate this in the body of the text. It’s a fascinating result, but curb your enthusiasm for now, there’s a lot yet to do. PD-1 Blockade in Mismatch […]

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Non-pseudoscience Cancer Cures

Another Step Closer to a True Generalizable “Cure for Cancer”

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer From “Nature: Medicine” https://www.nature.com/articles/s41591-018-0040-8 Immunotherapy using either checkpoint blockade or the adoptive transfer of antitumor lymphocytes has shown effectiveness in treating cancers with high levels of somatic mutations—such as melanoma, smoking-induced lung cancers and bladder cancer—with little effect in other common […]

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Non-pseudoscience Cancer Cures

Two Infants Treated with Universal Immune Cells Have Their Cancer Vanish

Two Infants Treated with Universal Immune Cells Have Their Cancer Vanish In a medical first, the children were treated with genetically engineered T-cells from another person. by Antonio Regalado January 25, 2017 Doctors in London say they have cured two babies of leukemia in the world’s first attempt to treat cancer with genetically engineered immune […]

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Non-pseudoscience Cancer Cures

Polio virus for Glioblastoma Multiforme

What ’60 Minutes’ Got Right And Wrong On Duke’s Polio Virus Trial Against Glioblastoma by David Kroll on Forbes.com An engineered version of the poliovirus has been in development for more than 20 years as a treatment for one of the most difficult-to-treat cancers, a brain tumor called glioblastoma multiforme, abbreviated GBM. A human safety […]

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Non-pseudoscience Cancer Cures

New Treatment for Advanced Leukemia (I told you so)

From Sky News Tests of a potentially revolutionary cancer therapy have had “extraordinary” results on terminally ill patients, scientists have revealed. In one study, more than nine out of ten participants with a severe form of leukaemia saw their symptoms completely vanish. Four out of five patients with some other blood cancers responded positively to […]

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Non-pseudoscience Cancer Cures

Incremental Advance in Immune Therapy for Melanoma

[Though not as striking as the abscopal effect stories that have come out recently in the context of metastatic melanoma, this story advances the notion that immune modulation is a viable approach to a generalizable treatment for cancer.   Although my hypothesis is that patient specific immune modulation (targeting the patient’s actual tumor markers and pointing the […]

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Non-pseudoscience Cancer Cures Steve's Blog

Abscopal Effect and Malignant Melanoma

[This one is a rare effect, but if they can just figure out how to trigger it consistently (research is ongoing) this would be a kickass weapon in the war against malignant melanoma and some other cancers.   A more general article on the abscopal effect can be found on Wikipedia, but here’s a quickie […]

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Non-pseudoscience Cancer Cures Steve's Blog

Measles and Multiple Myeloma

[Another interesting idea…if you know someone with refractory multiple myeloma, they may qualify for a clinical trial in vaccine therapy (take THAT, anti-vaxxers!)  –dr steve] from cnn.com A woman with an incurable cancer is now in remission, thanks, doctors say, to a highly concentrated dose of the measles virus. For 10 years, Stacy Erholtz, 49, battled multiple […]

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Non-pseudoscience Cancer Cures Steve's Blog

Striking Results With T-Cell Immunotherapy in Cervical Cancer

[I used to say we were 100 years away from a more generalized approach to cancer therapy.  In the end, barring some unforeseen breakthrough, cancer “cures” will come from the realm of immunology.  The immune system is perfectly appointed to eradicate cancer cell by cell, molecule by molecule, but it only works if it actually […]

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